Comparison of Risk Factors and survival of Type 1 and Type II Endometrial Cancers

نویسندگان

  • Tahira Y. Malik
  • Uzma Chishti
  • Aliya B. Aziz
  • Irfan Sheikh
چکیده

OBJECTIVE To compare risk factors and progression free survival of type 1 & 2 endometrial cancers. METHODS A retrospective analysis of 149 patients with early stage endometrial carcinoma treated between 1997 and 2012 in Aga Khan University Hospital, Karachi was performed. RESULTS A total of 149 patients were analyzed. Type I tumors accounted for 92% of cases in the study while 8% were type II tumors. The mean age, BMI, parity, co-morbidities (hypertension & Diabetes), family history and history of polycystic disease were comparable in both groups. Overall better survival (113 Vs 24 months) was observed for type I endometrial cancer. CONCLUSION Both types of endometrial cancer may share common etiologic factors. Despite the limitation of small numbers in one group this study confirms better survival in type 1 endometrial cancer.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Evaluation of HER2/neu Expression in High-Grade Endometrial Carcinoma and Its Clinicopathological Correlation

Background & Objective: Endometrial carcinoma (EC) has been traditionally classified into two distinct categories of low-grade and high-grade. Type I (low grade) EC, which constitutes the majority of cases, is linked to estrogen-related molecular pathways. But type II (high-grade) EC accounts for 10-20% of cases and behaves in an aggressive way. Pathologic and biological featur...

متن کامل

The Effect of Time-dependent Prognostic Factors on Survival of Non-Small Cell Lung Cancer using Bayesian Extended Cox Model

  Abstract Background: Lung cancer is one of the most common cancers around the world. The aim of this study was to use Extended Cox Model (ECM) with Bayesian approach to survey the behavior of potential time-varying prognostic factors of Non-small cell lung cancer. Materials and Methods: Survival status of all 190 patients diagnosed with Non-Small Cell lung cancer referring to hospitals in ...

متن کامل

Comparison of Random Survival Forests for Competing Risks and Regression Models in Determining Mortality Risk Factors in Breast Cancer Patients in Mahdieh Center, Hamedan, Iran

Introduction: Breast cancer is one of the most common cancers among women worldwide. Patients with cancer may die due to disease progression or other types of events. These different event types are called competing risks. This study aimed to determine the factors affecting the survival of patients with breast cancer using three different approaches: cause-specific hazards regression, subdistri...

متن کامل

P-158: ART and Gynecological Cancer: Report of Our Experiences and Literature Review

Background: Infertility is an important and common problem in couples that needs to assisted reproductive technology (ART) or the other drug therapies. Infertility has been known as a risk factor for ovarian cancer, breast cancer and endometrial cancer but there is a question about the relationship of these cancers to infertility itself or drugs and methods of infertility treatment. Materials a...

متن کامل

Prevalence and Risk Factors of Diabetes, Pre-Diabetes and Metabolic Syndrome in First-Degree Relatives of Patients with Type II Diabetes

Background & Aims: The aim of this study was to estimate the prevalence and risk factors for diabetes, pre-diabetes and metabolic syndrome in first-degree relatives(FDRs) of patients with type 2 diabetes. Methods: In a cross-sectional study between 2003 and 2005, 3228 of first-degree relatives of patients with type 2 diabetes (841 men and 2387 women) from Isfahan Endocrine and Metabolism Resear...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره 32  شماره 

صفحات  -

تاریخ انتشار 2016